DEFINITION
Tuberculosis (TB) disease is an infection caused by Mycobacterium Tuberculosis infection. Bacteria that are dormant can rise again and make more active tuberculosis.
ETIOLOGY
The cause is Tuberculosis Mycobacterium tuberculosis, the type of rod-shaped bacteria with length 1 - 4 / Um, thick and 0.3 - 0.6 / Um. Most of the bacteria consist of fatty acid (lipid). Lipid is what makes bacteria resistant to acid and more resistant to chemical and physical interference.
Bacteria can quickly die with the sun directly, but can survive several hours at the dark and humid. Nature of other bacteria is aerob.
PATHOGENESIS
1. Primary infection
Primary infection occurs when a person was first exposed to the TB bacteria, entri the droplet size is very small, so the system can pass defense mukosislier bronkus, and continue to run until the alveolus and settled there.
2. Post Primary Tuberculosis
Post-primary tuberculosis usually occurs after several months or years after primary infection.
Natural history of TB patients not treated:
- 50% died
- 25% will recover with your own body resistance is high
- 25% will become chronic cases, which remain infectious
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