parotitis 7

Diagnosis

Diagnosis can obtained when there are clear symptoms of infection parotitis epidemika on physical examination. Besides leukopenia with relative limfositosis, also found the increase in serum level amilase a peak after one week and then became normal again in 2 weeks.
When clinical symptoms are not clear, the diagnosis is based on: 2
1. There is virus in saliva, urine, likuor serebrospinalis or blood.
2. Serum Neutralization Test
3. Obtained antibody in the serum of antigen during S epidemic have symptoms of parotitis. Number of antibody reaches its peak at the beginning of the disease and then disappear within 6 - 12 months, while the antibody against the antigen or antigen virus get up to V peak in 1 month, settled in the next 6 months and then decrease in slow up to 2 years in a number of low and that remain.
When clinical manifestations limited to the manifestation of one of the lesi less common, the diagnosis is not so clear but suspected, especially during the epidemic. Laboratory test is not specific, usually leukopeni, with relatively limfositosis, but complications often cause leukositosis are polimorfonuklear level. Commonly have increased serum amylase, tend to increase parallel with swollen parotis and then return to normal in about 2 week.
Diagnosis depends on the etiology of virus isolation from saliva, urine, Spinal fluid and blood. Antibody serum against the S antigen peak at around 75% patients and can be detected at the time the symptoms appear. This antibody gradually disappears in 6-12 month. Antibody against the V antigen or virus usually reaches peak titer at about 1 month, remain stable for about 6 months, and then slowly decreased during the 2 years until the lower level, and then the titer is settled. The existence of anti-S titer and high titer of anti-V to a low during the acute stages, if not diagnosed meningoensefalitis, very prepossess parotitis infection, which would be strengthened if convalescent serum showed four times the increase of anti-V antibody is accompanied by little change in the titer of anti-antibody S.