Cirrosis Hepatis 3


Etiology

1. Hepatitis virus type B and C
2. Alcohol
3. Metabolic (hemokromatosis idiopathic, Wilson disease, deficiency alpha 1 anti tripsin, galaktosemia, tirosinemia congenital, DM, hoarding collagen disease)
4. Kolestasisi chronicles / bilier cirrhosis secondary intra and extra hepatic
5. Obstructs flow vena hepatic (Peny.vena occlusive, Budd Chiari syndrome, Perikarditis constrictive, heart pains right)
6. Interference immunologist
7. Toksik and drugs (mtx, INH, Metildopa)
8. Pintasusus smooth operation on Obesity
9. Malnutrition
10. Idiopathic

Sign and symptoms
Soebandiri criteria, when there is 5 of 7:
1. Spider nevi
2. Venectasi / vena collateral
3. Ascites (with or without edema feet)
4. Spelomegali
5. Varices esophagus (hemel)
6. Ratio of albumin: globulin inverted
7. Palmar eritema
Based on clinical manifestations:
1. Kompensata (not affect function hepar)
Fever intermittent
Spider nevi
Palmar eritema
Epitaxy's
Edema legs
Dyspepsia's
painful abdomen
Hepatosplenomegali
2. Dekompensata
Ascites
jaundice
physical weakness
Lost BB
Epistaksis
Hipotensi
Atropi gonadal

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