parotitis 3

Patofisiologi and Pathogenesis

On parotis gland saliva, especially in the channel there is a difference epitel cell swelling, widening the channel and the stoppage. When the testis infection then there is little bleeding and necrosis cells epitel tubuli seminiferus. In the pancreas sometimes there is a degeneration necrosis tissue.
After the entry and begin cell division in the respiratory tract, the virus was brought to the blood of many networks, including salivary gland to gland and the other the most prone.
The virus can isolated saliva for 6 days before and up to 9 days after emergence swollen salivary gland. Transmission probably not going longer than 24 hours before the emergence swollen or more slowly than 3 days after healed. The virus can isolated from urin since the first day to 14 after starting swollen salivary gland. The virus can isolated faring two days before to six days after going parotis gland enlargement. In the patients without parotis epidemic gland enlargement parotis, the virus can also isolated from faring.
Lifelong immunity usually accompany the infection or clinical subklinis, although the two infections have been documented. Antibody tranplasental presumably effective in an infant during the first 6-8 weeks. Infants born of mothers suffering from parotitis in the weeks before childbirth had parotitis may appear clinically at the time of the birth or illness at the time neonates.