juvenil diabetes: 4 insulin


Insulin
Insulin is a hormone that consists of a series of amino acid, is produced by beta cells pancreas gland. In normal circumstances, when there is excitement in the beta cells, insulin sintesis and then sekresi in blood according to the needs of the body for the regulation of blood glucose.
Insulin synthesis begins in the form of preproinsulin (insulin precursor hormone) on the reticulum endoplasmic beta cells. With the help of enzyme peptidase, preproinsulin to pro insulin solution so that the form, which is then gathered in the bubble-bubble (secretory vehicle) in these cells. Here, with the help of enzyme peptides, apart into pro insulin and insulin C-peptide (C-peptide) that they are ready to sekresi at the same time through the cell membrane.
Physiological mechanism of the above, is required for glucose metabolism during the process, in relation to the function of insulin in the process of glucose utilization in the body. Blood glucose level is increased, the main components that provide stimulus to the beta cells produce insulin, although some types of amino acids and drugs, can also have the same effect. Mechanism synthesis and insulin sekresi after the stimulus to the beta cell is quite complex, and can not fully be understood clearly.

No comments:

Post a Comment