juvenil diabetes: 2 etiology


Epidemiology
DM is a disease with great consequences to health and social. Not only because of the high prevalence of complications, but because cronic and a high death rate.
Prevalence of DM in the world continues to increase. In 1995, prevalence 4.0%. In the year 2025 is estimated to be 5.4%. In developing countries increased prevalence is more light. In 1995 it was found 84 million cases of DM and in the year 2025 this figure will increase to 228 million.
The occurrence of diabetes was 7 years before diagnosis, so morbidity and early mortality occurred in cases that are not detected.

Etiology and Pathogenesis
Developments in understanding the etiology and pathogenesis DM revitedthe previous classification. Although all types of DM by the hyperglycemia, but pathogenesis occurrence hyperglycemia very different. 2005 American Diabetes Association (ADA) to make the classification, the diabetes is type 4, among others, type 1 DM, type 2 DM, type DM, and DM in pregnancy. Diagnostic criteria of DM, according to the ADA in 2005 is:
1. When blood sugar 200 mg / dl if the typical complaints,
2. Fasting blood sugar 126 mg / dl.
3. Plasma glucose level 200 mg / dl at 2 hours after glucose load at 75 grams TTGO.
Diabetes mellitus is not a single form, but presumably is a heterogeneous group of aberration is the difference between the pattern and the genetic mechanism and etiology patofisiologi other disturbances that cause glucose tolerance. National Diabetes Data Group has put the classification category and diabetes glucose intolerance based on the knowledge of the present. This classification has been accepted and supported by various diabetes associations around the world by researchers and Pediatrics. Three main forms of diabetes and some forms of carbohydrate intolerance were identified: Type I Diabetes (Diabetes mellitus Juvenil), type II diabetes, and secondary diabetes.

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