tuberculosis 5

DIAGNOSIS

According to the American Thoracic Society, definitive diagnosis of tuberculosis tuberculosis is found with the bacteria Mycobacterium tuberculosis in sputum or tissue culture for tuberculosis.
Tuberculosis in the diagnosis of tuberculosis should be included clinical status, bacteriological status, and status radiologist status kemoterapI.
HANDLING
How Terapy pharmacology with Anti Tuberculosis Drugs (oat).
Principles of treatment:
TB drugs are given in the form of a combination of several types, in sufficient doses and appropriate for 6 - 8 weeks, so that all bacteria (including persistent bacteria) can be killed. Dose of intensive phase and continuation phase doses swallowed as a single dose, preferably on the stomach is empty.

TB treatment was given in 2 phases, namely:
1. Intensive phase.
Initial intensive phase, with activities bactericide that destroy the bacteria that split the population quickly. At this stage, the patient swallow the medicine every day and begins immediately to prevent the occurrence of resistance against all oat, especially rifampisin. When the intensive treatment phase is given exactly, the patient does not become contagious infectious within 2 weeks. Most people with TB BTA positive BTA become negative (conversion) at the end of the intensive treatment.
2. Advanced stage.
Advanced stage, with the sterilization of bacteria on short-term treatment or activities bakteriostatik on conventional treatment. At this stage, is important to kill bacteria, so preventing the occurrence of persistent relaps.

Type of Anti Tuberculosis Drugs (oat);
1. Isoniasid (H).
Known with INH, is bactericide, can kill bacteria 90% of the population in a few days treatment. This drug is very effective against bacteria in metabolic active, the germs that are growing. The recommended daily dose of 5 mg / kg of BB, while for intermittent treatment given 3 times a week dose of 10 mg / kg BB.
2. Rifampisin (R).
Bactericide be, can kill semi-dormant bacteria, which are not killed by isoniasid. Dose of 10 mg / kg of BB for the same treatment given daily or 3 times a week intermiten.
3. Pirasinamid (Z).
Are bactericide, the recommended daily dose 25 mg / kg of BB, while for intermittent treatment given 3 times a week with a dose of 35 mg / kg BB.
4. Streptomycin (S).
Are bakterisid. The recommended daily dose of 15 mg / kgBB medium-kan intermittent to treatment 3 times a week used the same dose.
5. Etambutol (E).
Are as bakteriostatik. The recommended daily dose of 15 mg / kg BB.

Oat Guide in Indonesia:
WHO and IUATLD (International Union Against Tuberculosis and lung Disease) guidelines recommend a standard of treatment with FDC tb:
1. Category Medicine
A. Category 1 (2HRZE / 4 H3R3)
Indications:
- People with a new positive TB Paru BTA
- People with new TB pulmo's BTA negative / positive rays (light & heavy)
- People with TB paru Extra
B. Category 2 (2HRZES / HRZE / 5 H3R3E3)
Indications:
- People with new TB Paru BTA positive relapse
- People with a new positive TB Paru BTA failed
- People with TB defaulter is used again with a positive BTA
C. Category 3 (2HRZ/4H3R3)
Indications:
- People with a negative BTA new and positive pain light rays.
- People with extra light tuberculosis, TB that is limfe gland, exudate unilateral pleuritis, TB skin, joints, and adrenal gland.