Patofisiologi
Infection of viral hepatitis type B / C causes liver inflammation. This causes inflammation necrosis covers a wide area (hepatoseluler), going collapse lobulus heart and stimulate the occurrence of this network, along with scar make septa fibrous diffuse and nodule liver cells. Although the etiology is, picture histologist same or nearly the same. And can be formed from cells that reticulum buffer collapse and changed so scar. Some of the cells to grow back and form nodule with different size and this causes distortion hepatic duct branching and disruption of blood flow and cause a porta hypertensive portal. The next stage occurs necrosis in inflammation and cell duktules, sinusoid, reticule endotel, going active fibrogenesis and septa. Collagen network fari reversible change becomes irreversible when the septa have a permanent aselular in the porta and parenkim heart.
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