Only a small proportion of lung cancer (about 10% -15% in men and 5% in women) are caused by substances that met or inhaled in the workplace. Working with asbestos, radiation, arsenic, chromate, nickel, klorometil ethers, mustard gas and coke oven emission can cause lung cancer, although usually only occurs in workers who also smoked.
The role of air pollution as a cause of lung cancer is still unclear. in more lung cancer patients in many urban areas air pollution than many who live in rural areas.
Lung cancer can also be associated with genetic where there is a change / mutation of several genes that play a role in lung cancer, namely: Proto oncogen, tumor supressor gene, Gene encoding enzyme. The occurrence of lung cancer based on the appearance of tumor suppressor genes in the genome (oncogene). The existence of the initiator of tumor suppressor genes changed by removing (deletions / del) or insertion (insertion / INS) some basa acid composition, appearance and / or erbB1 gene neu/rbB2 role in the anti-apoptosis (a mechanism for cells to die naturally programmed cell death). Change the look of this case gene causes the target cells in this case lung cells turn into cancer cells with the growth nature of the autonomic.
Cigarettes as well as an initiator and promoter known progresor and cigarettes are related (the largest) with the occurrence of lung cancer. Thus cancer is a genetic disease at the outset limited to target cells and then become aggressive in the surrounding tissue and even of other organs.
Diet. Several studies have reported that the low consumption of betakarotene, selenium and vitamin A causes high risk of lung cancer.
Sometimes lung cancer (particularly adenocarcinoma and alveolar cell carcinoma) occur in people who have lung scarring due to a lung disease, such as tuberculosis and fibrosis.
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